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Ri-Lei Yu

Ocean University of China

5 Yushan Road

Qingdao, 266003

China

SCHOLARLY PAPERS

11

DOWNLOADS

469

TOTAL CITATIONS

2

Scholarly Papers (11)

1.

Discovery of Anthraquinone-Triazene Derivatives as Novel Antitumor Agents Causing DNA Damage

Number of pages: 31 Posted: 27 May 2025
Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Ocean University of China, affiliation not provided to SSRN, Qingdao University of Science and Technology and Qingdao University of Science and Technology
Downloads 67 (907,769)

Abstract:

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Molecular docking, antiproliferative, electrochemical, UV-vis and fluorescence

2.

One-Pot Synthesis of Cysteine-Rich Peptide Via ‘Dpds’ Mediated Sulfur Exchange Reaction

Number of pages: 16 Posted: 02 Jan 2024
Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Ocean University of China, Qingdao University of Science and Technology and Qingdao University of Science and Technology
Downloads 64 (924,743)

Abstract:

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Disulfide bond, Dithiopyridine analogue, Cysteine-rich peptide, One-pot synthesis, Sulfur exchange reaction

3.

Reasonable Design and Synthesis of Novel Antitumor Agents Naphthalimide-Nitrosourea Derivatives Causing DNA Oxidative Damage Through Intercalation Mode

Number of pages: 35 Posted: 04 Feb 2025
Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Ocean University of China, Qingdao University of Science and Technology and Qingdao University of Science and Technology
Downloads 63 (942,565)

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Molecular docking, oxidative damage, UV-vis absorption, fluorescence spectra, gel electrophoresis

4.

Discovery of Novel Naphthylamide-Hydrazone Derived Antitumor Agents for the Electrochemical Detection of DNA Damage

Number of pages: 23 Posted: 26 Feb 2024
Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Ocean University of China, Qingdao University of Science and Technology and Qingdao University of Science and Technology
Downloads 56 (1,010,164)

Abstract:

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biosensor, anti-interference, mitonafide, amonafide, serums

5.

Design, Synthesis, and Bioactivity Study on Lissodendrins B Derivatives as Parp1 Inhibitor

Number of pages: 22 Posted: 21 Apr 2022
Ocean University of China, Ocean University of China, Ocean University of China, Ocean University of China, Ocean University of China and Ocean University of China
Downloads 55 (1,010,164)

Abstract:

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PARP inhibitor, anti-tumor activity, poly(ADP-ribose) polymerase activity, synthetic lethality, DNA damage

6.

Rational Design and Synthesis of Triazene-Amonafide Derivatives as Novel Potential Antitumor Agents Causing Oxidative Damage Towards DNA Through Intercalation Mode

Number of pages: 22 Posted: 15 Dec 2023
Qingdao University of Science and Technology, affiliation not provided to SSRN, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Ocean University of China, Qingdao University of Science and Technology and Qingdao University of Science and Technology
Downloads 38 (1,222,651)
Citation 2

Abstract:

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Electrochemical detection, DNA biosensor, naphthylimide, anti-interference, mouse and human serums

7.

Electrochemical Detection of DNA Damage Caused by Novel Potential 2-Nitroimidazole Naphthalimide-Based Hypoxia Tumor-Targeting Agent with Mimimum Side Effects

Number of pages: 15 Posted: 16 Feb 2022
Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qilu University of Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Ocean University of China, Qingdao University of Science and Technology and Qingdao University of Science and Technology
Downloads 32 (1,290,922)

Abstract:

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DNA electrochemical biosensor, oxidative damage, 2-nitroimidazole, 1, 8-naphthalimide, antitumor drug, DNA intercalator

8.

Targeted Preparation of Ace Inhibitory Hydrolysate and Rapid Screening of Ace Inhibitory Peptides Based on a Novel Deep Learning Model: A Computer-Assisted Experimental Study Method

Number of pages: 35 Posted: 15 May 2024
Ocean University of China, Jiangsu University of Technology, Ocean University of China, Ocean University of China, Ocean University of China, Ocean University of China, Ocean University of China, Ocean University of China, Ocean University of China and Ocean University of China
Downloads 30 (1,318,317)

Abstract:

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ACE, peptide, Virtual screen, Target preparation

9.

Design, Synthesis, and Biological Evaluation of Marine Lissodendrins B Analogues as Modulators of ABCB1-Mediated Multidrug Resistance

Number of pages: 41 Posted: 17 Mar 2023
Ocean University of China, Ocean University of China, Ocean University of China, Ocean University of China, Ocean University of China, Ocean University of China, Ocean University of China - Key Laboratory of Marine Drugs, Ministry of Education and Ocean University of China
Downloads 27 (1,359,097)

Abstract:

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Lissodendrins B analogues, Y-shaped scaffold, tetrahydroisoquinoline, multidrug resistance, ABCB1 inhibitors

10.

Naphthalimide-Nitrosourea Derivatives as Dual-Function Antitumor Agents for Exploration of Their Action Mechanisms and Chemical Degradation Process

Number of pages: 39 Posted: 22 Jul 2025
Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Ocean University of China, affiliation not provided to SSRN, Qingdao University of Science and Technology and Qingdao University of Science and Technology
Downloads 21 (1,448,301)

Abstract:

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Molecular docking, Molecular Dynamics Simulations, topo II, chemical degradation, DNA damage

11.

Tilmicosin Derivatives as Topoisomerase Ii Inhibitors: Rational Design, Synthesis, and Antibacterial Evaluation

Number of pages: 33 Posted: 23 May 2025
Qingdao University of Science and Technology, Qingdao University of Science and Technology, Qingdao University of Science and Technology, Ocean University of China, affiliation not provided to SSRN, Qingdao University of Science and Technology and Qingdao University of Science and Technology
Downloads 16 (1,509,872)

Abstract:

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Macrolides, Molecular docking, Molecular dynamics simulations, half-life, wound infection model