affiliation not provided to SSRN, University of Alabama at Birmingham, affiliation not provided to SSRN, City of Hope, University of Texas at Houston - Department of Lymphoma and Myeloma, Sarah Cannon Research Institute, University of Pennsylvania - Abramson Cancer Center, University of Wisconsin-Madison, affiliation not provided to SSRN, affiliation not provided to SSRN, Winship Cancer Institute, Emory University, Medical College of Wisconsin, affiliation not provided to SSRN and affiliation not provided to SSRN