University College London - Great Ormond Street Institute of Child Health, University College London - Great Ormond Street Institute of Child Health, affiliation not provided to SSRN, University College London - Great Ormond Street Institute of Child Health, University College London - Great Ormond Street Institute of Child Health, affiliation not provided to SSRN, University College London - Great Ormond Street Institute of Child Health, Imperial College London - Department of Computing, Hospital Necker, Enfants Malades - Oral and Maxillofacial Surgery Department and University College London