Shenzhen Polytechnic - Shenzhen Key Laboratory of Fermentation Purification and Analysis, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Shenzhen Polytechnic - Shenzhen Key Laboratory of Fermentation Purification and Analysis, Cape Breton University - Department of Chemistry, Cape Breton University - Department of Chemistry, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Cape Breton University - Department of Biology and Cape Breton University - Department of Chemistry