University of Edinburgh - Asthma UK Centre for Applied Research, University of Edinburgh, Perth Children’s Hospital, Tampere University - Tampere Center for Child, Adolescent and Maternal Health Research, Queen Mary University of London - Centre for Genomics and Child Health, Cincinnati Children's Hospital Medical Center, University of Turku, Milton Keynes University Hospital, University of Edinburgh - Royal Hospital for Sick Children, Royal Aberdeen Children's Hospital and University of Edinburgh