Sun Yat-Sen University (SYSU), Zhongshan School of Medicine, Sun Yat-Sen Memorial Hospital, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangxi Medical University - Department of Experimental Research, Sun Yat-Sen University (SYSU), Zhongshan School of Medicine, Sun Yat-Sen Memorial Hospital, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Beijing Normal University-Hong Kong Baptist University United International College - Division of Science and Technology, Guilin Medical University, Beijing Normal University-Hong Kong Baptist University United International College - Division of Science and Technology, Sun Yat-Sen University (SYSU), Zhongshan School of Medicine, Sun Yat-Sen Memorial Hospital, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Sun Yat-Sen University (SYSU), Zhongshan School of Medicine, Sun Yat-Sen Memorial Hospital, Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Beijing Normal University-Hong Kong Baptist University United International College - Division of Science and Technology, Hong Kong University of Science & Technology (HKUST) - Department of Computer Science and Engineering and Sun Yat-sen University (SYSU) - Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation