University of Toronto - Toronto Rehabilitation Institute, University of Regensburg - University Medical Center of Regensburg, University of Toronto - Toronto Rehabilitation Institute, University of Toronto - University Health Network, University of Regensburg - University Medical Center of Regensburg, IRCCS Istituto Auxologico Italiano - Department of Endocrine and Metabolic Diseases, University Hospital Regensburg - Center for Clinical Studies, IRCCS Fondazione Don Carlo Gnocchi, University of Milano-Bicocca - School of Medicine and Surgery, University of Toronto and University of Regensburg - University Medical Center of Regensburg