Harvard University - Dana-Farber Cancer Institute, affiliation not provided to SSRN, Harvard University - Dana-Farber Cancer Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Harvard University - Dana-Farber Cancer Institute, Harvard University - Dana-Farber Cancer Institute, Harvard University - Dana-Farber Cancer Institute, Imperial College London, affiliation not provided to SSRN, affiliation not provided to SSRN, Harvard University - Dana-Farber Cancer Institute, Harvard University - Dana-Farber Cancer Institute, Harvard University - Dana-Farber Cancer Institute, Harvard University - Dana-Farber Cancer Institute, Harvard University - Dana-Farber Cancer Institute, University of California, Los Angeles (UCLA), Harvard University - Dana-Farber Cancer Institute, Harvard University - Dana-Farber Cancer Institute, Harvard University - Dana-Farber Cancer Institute, Harvard University - Dana-Farber Cancer Institute, affiliation not provided to SSRN, MD Anderson Cancer Center - Department of Gastroenterology, Hepatology and Nutrition, affiliation not provided to SSRN, University of Kansas - Cancer Center, University of Kansas - University of Kansas Medical Center, Vanderbilt University, Vanderbilt University - Medical Center, Imperial College London, Harvard University - Dana-Farber Cancer Institute, Memorial Sloan Kettering Cancer Center, Harvard University - Dana-Farber Cancer Institute, Harvard University - Dana-Farber Cancer Institute and University of Oklahoma - Stephenson Cancer Center

Imperial College London - Hammersmith Hospital, CHA University - CHA Bundang Medical Center, Imperial College London - Hammersmith Hospital, Kindai University, Mount Sinai Health System - Division of Hematology/ Oncology, Mount Sinai Health System - Precision Immunology Institute, Mount Sinai Health System - Division of Hematology/ Oncology, University of Kansas - Cancer Center, University of Kansas - Cancer Center, IRCCS Humanitas Research Hospital, IRCCS Humanitas Research Hospital, IRCCS Humanitas Research Hospital, University of Vienna, University of Vienna, Medical University of Vienna - Vienna Hepatic Hemodynamic Laboratory, Royal Marsden NHS Foundation Trust, National Yang Ming University - Taipei Veterans General Hospital, University of Texas at Dallas - Southwestern Medical Center, University of Oklahoma - Stephenson Cancer Center, University of Pisa, University of Pisa, University of Pisa, University of Freiburg - Faculty of Medicine, Hannover Medical School - Department of Gastroenterology, Hepatology and Endocrinology, University of Hamburg - University Medical Center Hamburg-Eppendorf, University of Hamburg - University Medical Center Hamburg-Eppendorf, University of Hamburg - University Medical Center Hamburg-Eppendorf, University of Hamburg - University Medical Center Hamburg-Eppendorf, University Medical Center Mainz, Kindai University - Department of Gastroenterology and Hepatology, IRCCS Humanitas Research Hospital, University of Texas at Dallas - Division of Digestive and Liver Diseases, Imperial College London, Imperial College London - Hammersmith Hospital, Roche, CHA University - CHA Bundang Medical Center and Imperial College London

Imperial College London, affiliation not provided to SSRN, Harvard University - Dana-Farber Cancer Institute, affiliation not provided to SSRN, affiliation not provided to SSRN, Imperial College London, University of Copenhagen - Copenhagen University Hospital, affiliation not provided to SSRN, affiliation not provided to SSRN, Harvard University - Harvard Medical School and affiliation not provided to SSRN

Imperial College London - Hammersmith Hospital, Imperial College London - Hammersmith Hospital, University of Piemonte Orientale, University of Piemonte Orientale, Marmara University - School of Medicine, University of Piemonte Orientale, Imperial College London - Hammersmith Hospital and Imperial College London

Imperial College London, Imperial College London, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Imperial College London, Imperial College London, University of Piemonte Orientale, Fondazione Policlinico Universitario Agostino Gemelli IRCCS and University of Turin - Department of Oncology