King Abdullah University of Science and Technology (KAUST), University of Vigo, affiliation not provided to SSRN, affiliation not provided to SSRN, King Abdullah University of Science and Technology (KAUST), King Abdullah University of Science and Technology (KAUST), Max Planck Society for the Advancement of the Sciences - Max Planck Institute for Chemistry, King Abdullah University of Science and Technology (KAUST) - Computational Bioscience Research Center (CBRC) and King Abdullah University of Science and Technology (KAUST)