University of Cambridge - Wellcome Trust and MRC Cambridge Stem Cell Institute, University of Cambridge - Wellcome Trust and MRC Cambridge Stem Cell Institute, University of Cambridge - Molecular Immunity Unit, University of Liverpool - Institute of Infection Biology and Microbiomes, University of Liverpool - Institute of Infection Biology and Microbiomes, University of Cambridge - Wellcome Trust and MRC Cambridge Stem Cell Institute, University of Liverpool - Institute of Infection Biology and Microbiomes, University of Liverpool - Institute of Infection Biology and Microbiomes, University of Cambridge - National Institute of Health Research Global Health Research Group on Neurotrauma, Luton & Dunstable University Hospital NHS Foundation Trust - Department of Emergency Medicine, University of Cambridge - Academic Division of Neurosurgery, - Rudolf Virchow Center for Integrative and Translational Bioimaging, - Rudolf Virchow Center for Integrative and Translational Bioimaging, - Department of Gynecology and Obstetrics, University of Liverpool - Institute of Infection Biology and Microbiomes, University of Cambridge - Department of Veterinary Medicine, - Department of Gynecology and Obstetrics, Northwest Agricultural and Forestry University - College of Veterinary Medicine, University of Cambridge - Molecular Immunity Unit and University of Cambridge - Wellcome Trust and MRC Cambridge Stem Cell Institute