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Yu Yang Jiang

Tsinghua University - State Key Laboratory of Chemical Oncogenomics

SCHOLARLY PAPERS

7

DOWNLOADS

205

TOTAL CITATIONS

0

Scholarly Papers (7)

1.

Discovery Of Novel Nucleoside Derivatives as Selective Lysine Acetyltransferase P300 Inhibitors for Cancer Therapy

Number of pages: 9 Posted: 20 Dec 2023
Changsha Medical University, Shenzhen Kivita Innovative Drug Discovery Institute, Tsinghua University - Tsinghua Shenzhen International Graduate School, University College London, Changsha Medical University and Tsinghua University - State Key Laboratory of Chemical Oncogenomics
Downloads 55 (1,041,696)

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histone acetyltransferases, p300 inhibitor, nucleoside scaffold, antitumor

2.

Design, Synthesis and Biological Evaluation of Dual JMJD3 and HDAC Inhibitors for Potential Cancer Therapy

Number of pages: 40 Posted: 17 Mar 2023
Tsinghua University, Shenzhen University, Tsinghua University, Shenzhen University, Tsinghua University, Shenzhen Kivita Innovative Drug Discovery Institute, Shenzhen University and Tsinghua University - State Key Laboratory of Chemical Oncogenomics
Downloads 37 (1,236,159)

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JMJD3, HDAC, Dual inhibitor, antitumor, Structure activity relationship analysis

3.

A high-sensitivity and matrix-resistant LC–MS method for accurate quantification of adipic acid in fungal microplastic degradation systems

Number of pages: 17 Posted: 20 Feb 2026
affiliation not provided to SSRN, Tsinghua University - Tsinghua Shenzhen International Graduate School, South China Normal University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and Tsinghua University - State Key Laboratory of Chemical Oncogenomics
Downloads 31 (1,399,036)

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microplastics, Fungal biodegradation, Adipic acid, LC-MS/MS, method development, Method validation

4.

Design and Synthesis of C-Mesenchymal Epithelial Transition Factor (C-Met) and Histone Deacetylase (Hdac) Dual Inhibitors for the Treatment of Breast Cancer

Number of pages: 21 Posted: 03 Jun 2024
Tsinghua University, affiliation not provided to SSRN, Tsinghua University, Tsinghua University, affiliation not provided to SSRN, Nankai University - State Key Laboratory of Medicinal Chemical Biology, affiliation not provided to SSRN, affiliation not provided to SSRN, Shenzhen University, affiliation not provided to SSRN and Tsinghua University - State Key Laboratory of Chemical Oncogenomics
Downloads 29 (1,345,526)

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breast cancer, c-Mesenchymal-to-epithelial transition, Histone deacetylase, Dual inhibitors, antitumor

5.

Enhanced Metagenomic Deep Learning for Disease Prediction and Reproducible Signature Identification by Restructured Microbiome 2D-Representations

Number of pages: 48 Posted: 06 Jun 2022
Tsinghua University - State Key Laboratory of Chemical Oncogenomics, Tsinghua University - State Key Laboratory of Chemical Oncogenomics, Tsinghua University - State Key Laboratory of Chemical Oncogenomics and Tsinghua University - State Key Laboratory of Chemical Oncogenomics
Downloads 28 (1,345,526)

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metagenomic, biomarker, disease prediction, multichannel, 2D-representations, MEGMA, AggMapNet

6.

Design and Synthesis of c-Met/PARP1 Dual-Target Inhibitors for the Treatment of BRCA Wild-Type TNBC

Number of pages: 28 Posted: 05 Dec 2025
Tsinghua University, Tsinghua University, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Tsinghua University - Tsinghua Shenzhen International Graduate School, affiliation not provided to SSRN, Tsinghua University - Tsinghua Shenzhen International Graduate School, affiliation not provided to SSRN, affiliation not provided to SSRN and Tsinghua University - State Key Laboratory of Chemical Oncogenomics
Downloads 25 (1,436,435)

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c-Met, PARP1, Dual target inhibitor, BRCA Wild-Type TNBC

7.

Deep Learning of 2D-Restructured Gene Expression Representations for Improved Low-Sample Therapeutic Response Prediction

Posted: 08 Mar 2023
Tsinghua University, National University of Singapore (NUS), Tsinghua University - State Key Laboratory of Chemical Oncogenomics, Shenzhen University, Tsinghua University - State Key Laboratory of Chemical Oncogenomics and Tsinghua University

Abstract:

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therapeutic response prediction, low-sample, gene expression, deep learning, transcriptome