Tohoku University, Graduate School of Medicine, Department of Cardiovascular Medicine, Tohoku University, Graduate School of Medicine, Department of Cardiovascular Medicine, Robert Bosch Hospital, Robert Bosch Hospital, University of Glasgow, University of Glasgow - Institute of Cardiovascular and Medical Sciences, Università Vita-Salute San Raffaele - San Raffaele Hospital, Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Department of Cardiovascular and Thoracic Sciences, St George’s University London, University of Florida - Center for Regenerative Medicine, National Research Council (CNR), Robert Bosch Hospital, Tohoku University, Graduate School of Medicine, Department of Cardiovascular Medicine, University of Adelaide - Faculty of Health Sciences, Cedars-Sinai Medical Center and Tohoku University, Graduate School of Medicine, Department of Cardiovascular Medicine