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Mingxu Ma

Yantai University

32, Qingquan RD

Laishan District

Yantai, 264005

China

  • Yantai University

SCHOLARLY PAPERS

4

DOWNLOADS

310

TOTAL CITATIONS

1

Scholarly Papers (4)

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1.

Discovery of Novel, Potent Polo-Like Kinase 1 (PLK1) Inhibitors for the Treatment of Colorectal Cancer

Number of pages: 30 Posted: 03 Feb 2023
Jing Lu, Hui Lei, Xinfa Bai, Wenyan Wang, Chunjiao Liu, Yifei Yang, Fangxia Zou, Guangying Du, Xin Wang, Cuicui Sun, Lisha Yu, Mingxu Ma, Liang Ye, Hongbo Wang, Jingwei Tian and jianzhao zhang
Yantai University, R & D Center, Luye Pharma Group Ltd., R & D Center, Luye Pharma Group Ltd., Yantai University, Yantai University, Yantai University, Yantai University, Yantai University, Yantai University, R & D Center, Luye Pharma Group Ltd., R & D Center, Luye Pharma Group Ltd., Yantai University, Binzhou Medical University, Yantai University, Yantai University and Yantai University
Downloads 86 (783,685)

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colorectal cancer, PLK1 inhibitor, Core scaffold hopping, structure-activity relationship

2.

Discovery of the Thieno[2,3-d]Pyrimidine-2,4-Dione Derivative 21a: A Potent and Orally Bioavailable Gonadotropin-Releasing Hormone Receptor Antagonist

Number of pages: 43 Posted: 15 Jun 2022
Fangxia Zou, Yao Wang, Dawei Yu, Chunjiao Liu, Jing Lu, Min Zhao, Mingxu Ma, Wenyan Wang, Wanglin Jiang, Yonglin Gao, Rui Zhang, Jianzhao Zhang, Liang Ye and Jingwei Tian
Yantai University, Yantai University, R & D Center (Luye Pharma Group Ltd.), Yantai University, Yantai University, Yantai University, Yantai University, Yantai University, Binzhou Medical University, Yantai University, R & D Center (Luye Pharma Group Ltd.), Yantai University, Binzhou Medical University and Yantai University - Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong
Downloads 84 (783,685)

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Gonadotropin-releasing hormone, oral bioavailability, pharmacokinetic, structure and activity

3.

A Novel Scaffold Long-Acting Selective Estrogen Receptor Antagonist and Degrader with Superior Preclinical Profile Against Er+ Breast Cancer

Number of pages: 49 Posted: 05 Sep 2023
Bingsi Wang, Mingxu Ma, Yusen Dai, Pengfei Yu, Liang Ye, Wenyan Wang, Chunjie Sha, Huijie Yang, Yingjie Yang, Yunjing Zhu, Lin Dong, Shujuan Wei, Linlin Wang, Jingwei Tian and Hongbo Wang
Yantai University, Yantai University, Luye Pharma Group Ltd., Binzhou Medical University, Binzhou Medical University, Yantai University, Luye Pharma Group Ltd., Luye Pharma Group Ltd., Luye Pharma Group Ltd., Luye Pharma Group Ltd., Luye Pharma Group Ltd., Luye Pharma Group Ltd., Shandong University - School of Business, Yantai University - Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong and Yantai University - Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University)
Downloads 80 (809,932)
Citation 1

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Hydrophobic tags, THC derivatives, Selective estrogen receptor down-regulator/antagonist, Long-acting, Anticancer agents, breast cancer

4.

Improving the Treatment of Depression with Favorable Efficacy and Safety Profiles: Synthesis and Evaluation of Neuroactive Steroids with Novel Pharmacophore at C-21 as the (Γ-Aminobutyric Acid)A Receptor Positive Allosteric Modulators

Number of pages: 49 Posted: 15 May 2024
Mingxu Ma, Hengwei xu, Liang Ye, Chunmei Li, Haibo Zhu, Wanglin Jiang, Wenyan Wang, Huijie Yang, Yingjie Yang, Yao Wang and Jingwei Tian
Yantai University, Yantai University, Binzhou Medical University, Yantai University, Binzhou Medical University, Binzhou Medical University, Yantai University, Luye Pharma Group Ltd., Luye Pharma Group Ltd., affiliation not provided to SSRN and Yantai University - Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong
Downloads 60 (970,490)

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treatment of depression, (γ-aminobutyric acid)A receptor positive allosteric modulators, neuroactive steroids, novel pharmacophore, favorable efficacy and safety profiles