Institute Pasteur de Lille - Prevention in Health and Longevity Centre, Hospital General Virgen del Rocío - Internal Medicine Service, University of Seville - Clinical Epidemiology and Vascular Risk, University of Granada - Department of Statistics and Operational Research, Hospital General Virgen del Rocío - Clinical Documentation Service, University of Seville - Institute of Biomedicine of Seville, Carlos III Institute of Health - National Center for Epidemiology and University of Seville - Institute of Biomedicine of Seville