Chang Gung University, Chang Gung University - Division of Reconstructive Microsurgery, National Taipei University of Technology - Department of Chemical Engineering and Biotechnology, Chang Gung University - Chang Gung Memorial Hospital, National Taiwan University - Department of Biomedical Engineering, National Taiwan University - Department of Biomedical Engineering, National Taiwan University - College of Medicine, National Taipei University of Technology - Department of Chemical Engineering and Biotechnology and National Taiwan University - Department of Biomedical Engineering