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Manish C. Choudhary

Harvard University - Massachusetts Consortium on Pathogen Readiness

Harvard University - Department of Medicine

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Scholarly Papers (1)

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S:D614G and S:H655Y are Gateway Mutations that Act Epistatically to Promote SARS-CoV-2 Variant Fitness

Number of pages: 54 Posted: 17 May 2023
Leonid Yurkovetskiy, Shawn Egri, Chaitanya Kurhade, Marco A. Diaz-Salinas, Javier A. Jaimes, Thomas Nyalile, Xuping Xie, Manish C. Choudhary, Ann Dauphin, Jonathan Li, James Munro, Pei-Yong Shi, Kuang Shen and Jeremy Luban
University of Massachusetts Worcester - Program in Molecular Medicine, University of Massachusetts Worcester - Program in Molecular Medicine, University of Texas Medical Branch-Galveston - Department of Biochemistry and Molecular Biology, University of Massachusetts Worcester - Department of Microbiology and Physiological Systems, University of Massachusetts Worcester - Program in Molecular Medicine, University of Massachusetts Worcester - Program in Molecular Medicine, University of Texas Medical Branch-Galveston - Department of Biochemistry and Molecular Biology, Harvard University - Massachusetts Consortium on Pathogen Readiness, University of Massachusetts Worcester - Program in Molecular Medicine, Harvard University - Massachusetts Consortium on Pathogen Readiness, University of Massachusetts Worcester - Department of Microbiology and Physiological Systems, University of Texas Medical Branch-Galveston - Department of Biochemistry and Molecular Biology, University of Massachusetts Worcester - Program in Molecular Medicine and University of Massachusetts Medical School - Program in Molecular Medicine
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SARS-CoV-2, COVID-19, coronavirus, variants, Spike protein, epistasis, Evolution, ACE2, pandemic, infectivity, S:Q613H, S:D614G, S:H655Y