New York University (NYU) - Tandon and School of Medicine, University of Catania - Department of Physics and Astronomy, University of Catania - Department of Clinical and Experimental Medicine, Shanghai University of Medicine and Health Sciences, University of Catania, New York University (NYU) - Grossman School of Medicine, University of Catania, New York University (NYU) - Grossman School of Medicine, Red Cross Blood Bank Foundation Curaçao and University of Catania - Department of Clinical and Experimental Medicine