Guangbo Ge

Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology

SCHOLARLY PAPERS

8

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306

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Scholarly Papers (8)

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1.

Astragalus Polysaccharide Ameliorates Vascular Endothelial Dysfunction by Stimulating Macrophage M2 Polarization Via Potentiating Nrf2/HO-1 Signaling Pathway

Number of pages: 18 Posted: 22 Sep 2022
Wenjun Sha, Bei Zhao, Huizhen Wei, Yunyi Yang, Hongping Yin, Jie Gao, Weiwei Zhao, Wenwen Kong, Guangbo Ge and Tao Le
Shanghai University of Traditional Chinese Medicine - Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine - Putuo Hospital, Shanghai University of Traditional Chinese Medicine, Anhui Medical University, Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology and Shanghai University of Traditional Chinese Medicine - Putuo Hospital
Downloads 56 (803,941)

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Astragalus polysaccharide (APS), macrophage polarization, Nrf2/HO-1 signaling pathway, Vascular endothelial dysfunction, diabetes vascular complications

2.

Protective Effects and Regulatory Mechanisms of Shen-Shuai-Yi Recipe on Renal Fibrosis in Unilateral Ureteral Obstruction-Induced Mice

Number of pages: 28 Posted: 23 May 2023
Pinglan Lin, Tao-tao Weng, Lian-xiang Duan, Lin-zhang Zhang, Xia Wei, Sheng-lan Qi, Jia-wen You, Yu Cao, Guangbo Ge, Wei Liu, Xiao-li He and Jing Hu
Shanghai Academy of Traditional Chinese Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai Academy of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology, Shanghai University of Traditional Chinese Medicine - Shuguang Hospital, Shanghai University of Traditional Chinese Medicine and Shanghai Academy of Traditional Chinese Medicine
Downloads 52 (833,387)

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renal fibrosis, chronic kidney disease, ureteral unilateral obstruction, Shen-shuai-yi recipe, signal transducer and activator of transcription 3

3.

Discovery and Characterization of the Covalent SARS-CoV-2 3clpro Inhibitors from Ginkgo Biloba Extract Via Integrating Chemoproteomic and Biochemical Approaches

Number of pages: 57 Posted: 24 Jan 2023
Guangbo Ge, Yani Zhang, Guang-Hao Zhu, Wei Liu, Yuan Xiong, Qing Hu, Xiao-Yu Zhuang, Gui-Hua Jia and Wei-Dong Zhang
Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine - Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine and Shanghai University of Traditional Chinese Medicine
Downloads 47 (873,401)

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SARS-CoV-2 3CLpro, covalent inhibitors, Ginkgo biloba extract 50 (GBE50), chemoproteomic profiling, anti-CoV agents

4.

Synthesis and SAR Study of Chloro-Retrochalcone Derivatives as Dipeptidyl Peptidase 4 Inhibitors with Anti-Inflammatory Effects

Number of pages: 17 Posted: 10 Apr 2023
Ci-qin Li, Jinhui Shi, Jie Mu, Anqi Wang, Li-wei Zou and Guangbo Ge
Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine - Institute of Interdisciplinary Integrative Medicine Research and Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology
Downloads 45 (890,480)

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DPP4, chalcones, structure-activity relationship, anti-inflammatory agents

5.

Qing-Fei-Pai-Du-Tang, a Chinese Medicine Formula, Ameliorates Lipopolysaccharide-Induced Acute Lung Injury Through Attenuating Pulmonary Microcirculatory Disturbances Via Multi-Target Regulation in Rats

Number of pages: 63 Posted: 03 Dec 2024
Shu-Ya He, Chun-Shui Pan, Li Yan, Ping Huang, Lu-Lu Yan, Rong Huang, Quan Li, Xin-Mei Huo, Jian Liu, Jing-Yu Fan, Wei Liu, Chao-Ran Wang, Guangbo Ge, Kai Sun and Jingyan Han
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Shanghai University of Traditional Chinese Medicine - Shuguang Hospital, affiliation not provided to SSRN, Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology, Peking University and Peking University - Department of Integration of Chinese and Western Medicine
Downloads 39 (955,640)

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leukocyte adhesion, microvascular hyperpermeability, junction protein, Caveolae, Mitochondrial dysfunction, adhesion molecule

6.

Discovery of 4'-Trifluoromethylchalcones As Novel, Potent and Selective hCYP1B1 Inhibitors Without Concomitant AhR Agonist Effect

Number of pages: 18 Posted: 24 Apr 2023
Yue Wu, Jinhui Shi, Huizhen Wei, Jia-Hao Gong, Zhao-Bin Guo, Zi-Ru Dai and Guangbo Ge
Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College (CAMS & PUMC) - Institute of Medicinal Plant Development and Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology
Downloads 27 (1,074,007)

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CYP1B1, chalcones, structure-activity relationships, anti-migration agent

7.

Cycloastragenol Inhibits Colorectal Cancer Metastasis by Attenuating the Activation of Pro-Tumor Macrophages Via Extracellular Vesicles-Mediated Glutamine-Γ-Aminobutyric Acid Metabolism

Number of pages: 22 Posted: 23 Apr 2025
Jing Zhou, Ling Li, Yunzhou Pu, Lei Tang, Tian Tian, Guang-Hao Zhu, Hui Zhang, Guangbo Ge, Qing Ji and Hong-Shan Li
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology, affiliation not provided to SSRN and Chinese Academy of Sciences (CAS)
Downloads 22 (1,134,815)

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Cycloastragenol, Tumor metastasis, Macrophages, extracellular vesicles, γ-aminobutyric acid

8.

Uncovering the Naturally Occurring Covalent Inhibitors of Sars-Cov-2 Mpro from the Chinese Medicine Sappanwood and Deciphering Their Synergistic Anti-Mpro Effects

Number of pages: 27 Posted: 20 Dec 2024
Qing Hu, Yiwen Zhang, Ya-Ni Zhang, Guang-Hao Zhu, Peng-Cheng Chen, Wei Liu, Xiao-Ping Hu, Fei-Feng Song, Zongfu Pan, Shui-Lian Zheng, Nong-Er Shen, Guangbo Ge and Ping Huang
affiliation not provided to SSRN, affiliation not provided to SSRN, Shanghai University of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, affiliation not provided to SSRN, Shanghai University of Traditional Chinese Medicine, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Shanghai University of Traditional Chinese Medicine - Shanghai Frontiers Science Center for Traditional Chinese Medicine Chemical Biology and affiliation not provided to SSRN
Downloads 18 (1,184,116)

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SARS-CoV-2 Mpro, sappanwood extract (SWE), covalent inhibitors, hematoxylin, brazilin