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Patrick Joseph Gillespie

Indiana University - Department of Medical and Molecular Genetics

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Succinyl-CoA Synthetase Deficiency in Mouse Forebrain Results in Hyper-Succinylation With Perturbed Neuronal Transcriptional Regulation and Metabolism

Number of pages: 57 Posted: 18 Aug 2022
Makayla Suzanne Anderson, Emma H. Doud, Hongyu Gao, Duojiao Chen, Edward Simpson, Patrick Joseph Gillespie, Xiaona Chu, Marcus James Miller, Yue Wang, Yunlong Liu, Amber L. Mosley and Brett H. Graham
Indiana University - Department of Medical and Molecular Genetics, Indiana University - Department of Biochemistry and Molecular Biology, Indiana University - Center for Computational Biology and Bioinformatics, Indiana University - Center for Computational Biology and Bioinformatics, Indiana University - Center for Computational Biology and Bioinformatics, Indiana University - Department of Medical and Molecular Genetics, Indiana University - Department of Medical and Molecular Genetics, Indiana University - Department of Medical and Molecular Genetics, Indiana University - Department of Medical and Molecular Genetics, Indiana University - Center for Computational Biology and Bioinformatics, Indiana University - Department of Biochemistry and Molecular Biology and Indiana University - Department of Medical and Molecular Genetics
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Post-translational modification, protein-acylation, TCA cycle, succinyl-CoA synthetase, Succinylation, Electron transport chain, chromatin, neurons, metabolism, ATAC-sequencing, RNA-sequencing, mass spectrometry