University of Milano-Bicocca, University of Milano-Bicocca, Fondazione IRCCS Istituto Nazionale dei Tumori - Department of Research, Fondazione IRCCS Istituto Nazionale dei Tumori, Fondazione IRCCS Istituto Nazionale dei Tumori, Fondazione IRCCS Istituto Nazionale dei Tumori, Fondazione IRCCS Istituto Nazionale dei Tumori, Fondazione IRCCS Istituto Nazionale dei Tumori, Fondazione IRCCS Istituto Nazionale dei Tumori, Fondazione IRCCS Istituto Nazionale dei Tumori - Department of Research and University of Milano-Bicocca

IRCCS Istituto Ortopedico Rizzoli di Bologna - Osteoncology, Bone and Soft Tissue Sarcomas and Innovative Therapies, IRCCS Istituto Ortopedico Rizzoli di Bologna, University of Bordeaux - Institut Bergonié, GlaxoSmithKline, University of Texas at Houston - MD Anderson Cancer Center, University College London - University College London Hospitals NHS Foundation Trust, Fondazione IRCCS Istituto Nazionale dei Tumori, Royal Marsden NHS Foundation Trust, Harvard University - Dana-Farber Cancer Institute, Universidad Autónoma de Madrid - FIIS-Fundacion Jimenez Diaz University Hospital, University of Seville - Institute of Biomedicine of Seville, General Hospital, Prato, Candiolo Cancer Institute, IRCCS Regina Elena National Cancer Institute, Istituto Oncologico Veneto – IRCCS, Yeshiva University - Montefiore Medical Center, Fondazione IRCCS Istituto Nazionale dei Tumori - Department of Medical Oncology, Universidad Autónoma de Madrid - FIIS-Fundacion Jimenez Diaz University Hospital, University of Lausanne - Lausanne University Hospital, Kantonsspital St Gallen, IRCCS Istituto Ortopedico Rizzoli di Bologna, University of Seville - Institute of Biomedicine of Seville, IRCCS Istituto Ortopedico Rizzoli di Bologna, University Hospital General de Villalba, Harvard University - Dana-Farber Cancer Institute, University Campus Bio-Medico, IRCCS Istituto Ortopedico Rizzoli di Bologna, IRCCS Istituto Ortopedico Rizzoli di Bologna, IRCCS Istituto Ortopedico Rizzoli di Bologna, IRCCS Istituto Ortopedico Rizzoli di Bologna, University of Padua - Department of Medicine, IRCCS Istituto Ortopedico Rizzoli di Bologna, IRCCS Istituto Ortopedico Rizzoli di Bologna, University of Padua - Department of Medicine, IRCCS Istituto Ortopedico Rizzoli di Bologna, Fondazione IRCCS Istituto Nazionale dei Tumori - Department of Medical Oncology and University Campus Bio-Medico

affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Charité - Universitätsmedizin Berlin, affiliation not provided to SSRN, Netherlands Cancer Institute, affiliation not provided to SSRN, University of Copenhagen - Copenhagen University Hospital, Fondazione IRCCS Istituto Nazionale dei Tumori, affiliation not provided to SSRN, Fondazione IRCCS Istituto Nazionale dei Tumori, Centro Hospitalar Universitário Lisboa Norte (CHLN), Fondazione IRCCS Istituto Nazionale dei Tumori, affiliation not provided to SSRN, affiliation not provided to SSRN, University College London - University College London Hospitals NHS Foundation Trust, University of Heidelberg, Fondazione IRCCS Istituto Nazionale dei Tumori - Department of Medical Oncology, Netherlands Cancer Institute and Hospital Clinico San Carlos