Baylor University - Department of Molecular and Human Genetics, Stanford University - Department of Genetics, Columbia University - Department of Chemical Engineering, Washington University in St. Louis - Department of Biochemistry and Molecular Biophysics, University of California, Berkeley - Molecular Biophysics and Integrated Bioimaging Division, Stanford University - Genetics Department, Stanford University - Genetics Department, Stanford University - Genetics Department, University of Queensland - Clem Jones Centre for Ageing Dementia Research, VIB Proteomics Core, VIB-UGent Center for Medical Biotechnology, University of California, Berkeley - Molecular Biophysics and Integrated Bioimaging Division, Stanford University - Department of Biochemistry, Stanford University - Department of Biochemistry, Federal University of São Paulo (UNIFESP) - Department of Pharmacology, The Scripps Research Institute - Department of Integrative Structural and Computational Biology, University of California, Berkeley - Molecular Biophysics and Integrated Bioimaging Division, Federal University of São Paulo (UNIFESP) - Department of Pharmacology, Stanford University - Genetics Department, Vlaams Instituut voor Biotechnologie (VIB) - VIB-UGent Center for Inflammation Research, Columbia University - Department of Chemical Engineering, Washington University in St. Louis - Department of Biochemistry and Molecular Biophysics and Stanford University - Genetics Department