Cardiff University, Cardiff University, Cardiff University, Northwestern Polytechnic University (NPU), Wuhan iRegene Therapeutics Co., Ltd, Wuhan iRegene Therapeutics Co., Ltd, Huazhong Agricultural University - College of Biomedicine and Health, Huazhong Agricultural University - College of Biomedicine and Health, University of Cambridge, Huazhong University of Science and Technology - Department of Medical Oncology, Huazhong University of Science and Technology - Hubei Cancer Hospital, Huazhong University of Science and Technology, Northumbria University - Faculty of Engineering and Environment, Northumbria University, Cardiff University - School of Medicine, Dalian University of Technology, Cardiff University and Cardiff University - Department of Electrical and Electronic Engineering