University of Florence, University of Florence, University of Florence, affiliation not provided to SSRN, University of Florence, affiliation not provided to SSRN, University of Florence, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Fondazione Policlinico Universitario A. Gemelli IRCCS - COU of Dermatology, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Perugia, University of Florence and National Research Council (CNR)