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Vashir Afshar-Kharghan

University of Southern California - Keck School of Medicine

SCHOLARLY PAPERS

2

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71

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Scholarly Papers (2)

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1.

Single Cell Clonotypic and Transcriptional Evolution of Multiple Myeloma Precursor Disease

Number of pages: 68 Posted: 09 Nov 2022
Minghao Dang, Guangchun Han, Hans C. Lee, Krina K. Patel, Sheeba K. Thomas, Dapeng Hao, Yanshuo Chu, Melody Becnel, Donna M. Weber, Pei Lin, Zuzana Lutter-Berka, David Berrios Nolasco, Xingzhi Song, Jianhua Zhang, P. Andrew Futreal, Yurany Moreno Rueda, David Symer, Michael Green, Cristhiam Rojas Hernandez, Michael Kroll, Vashir Afshar-Kharghan, Libere J. Ndacayisaba, Peter Kuhn, Sattva S. Neelapu, Robert Z. Orlowski, Linghua Wang and Elisabet E. Manasanch
University of Texas at Houston - Department of Genomic Medicine, University of Texas at Houston - Department of Genomic Medicine, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Genomic Medicine, University of Texas at Houston - Department of Genomic Medicine, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Hematopathology, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Genomic Medicine, University of Texas at Houston - Department of Genomic Medicine, University of Texas at Houston - Department of Genomic Medicine, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Southern California - Keck School of Medicine, University of Southern California - Keck School of Medicine, University of Southern California - Keck School of Medicine, University of Southern California, University of Southern California, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Lymphoma and Myeloma, University of Texas at Houston - Department of Genomic Medicine and University of Texas at Houston - Department of Lymphoma and Myeloma
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single-cell RNA sequencing (scRNAseq), multiple myeloma (MM), monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), single-cell B cell receptor sequencing (scBCR-seq), plasma cells (PCs), intra-tumoral heterogeneity (ITH), tumor microenvironment (TME), hyperdiploid (HY), non-hyperdiploid (non-HY)

2.

Genes with a significant deficit of loss-of-function mutations in lung tumors

Number of pages: 21 Posted: 11 Jun 2026
Ivan P. Gorlov, Olga Y. Gorlova, Yong Li, Vashir Afshar-Kharghan and Christopher I. Amos
affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Southern California - Keck School of Medicine and affiliation not provided to SSRN
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loss-of-function mutations, cancer essential genes, lung cancer, somatic mutation analysis, selective constraint