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Yuka Kanno

Government of the United States of America - Lymphocyte Cell Biology Section

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Differential Requirement of 3D Genomic Organization for the  Mdm1-Il22-Ifng Locus Regulation in Adaptive Versus Innate Responses

Number of pages: 48 Posted: 06 Jan 2023
Chunhong Liu, Hiroyuki Nagashima, Nilisha Fernando, Sadie Signorella, Will Montgomery, Ai Ing Lim, Oliver Harrison, Victor Bass, Lauren Reich, Chen Yao, Hong-Wei Sun, Stephen R. Brooks, Kan Jiang, Vijayaraj Nagarajan, Rachael Phillips, Yohei Mikami, Caleb A. Lareau, Yuka Kanno, Dragana Jankovic, Martin J. Aryee, Aleksandra Pekowska, Yasmine Belkaid, John O’Shea and Han-Yu Shih
Government of the United States of America - Neuro-Immune Regulome Unit, Government of the United States of America - Lymphocyte Cell Biology Section, Government of the United States of America - Neuro-Immune Regulome Unit, Government of the United States of America - Neuro-Immune Regulome Unit, Government of the United States of America - Neuro-Immune Regulome Unit, Government of the United States of America - Metaorganism Immunity Section, Government of the United States of America - Metaorganism Immunity Section, Government of the United States of America - Neuro-Immune Regulome Unit, Government of the United States of America - Neuro-Immune Regulome Unit, Government of the United States of America - Lymphocyte Cell Biology Section, Government of the United States of America - Biodata Mining and Discovery Section, Government of the United States of America - Biodata Mining and Discovery Section, Government of the United States of America - Biodata Mining and Discovery Section, Government of the United States of America - Neuro-Immune Regulome Unit, Government of the United States of America - Lymphocyte Cell Biology Section, Government of the United States of America - Lymphocyte Cell Biology Section, Massachusetts Institute of Technology and Harvard University - Broad Institute, Government of the United States of America - Lymphocyte Cell Biology Section, Government of the United States of America - Immunoparasitology Unit, Massachusetts Institute of Technology and Harvard University - Broad Institute, Polish Academy of Sciences (PAS) - Nencki Institute of Experimental Biology, National Institutes of Health - Metaorganism Immunity Section, Government of the United States of America - Lymphocyte Cell Biology Section and Government of the United States of America - Neuro-Immune Regulome Unit
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Abstract:

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Interferon-gamma (IFN-g), interleukin-22 (IL-22), Innate lymphoid cells (ILCs), super-enhancers (SEs), lymphocytic choriomeningitis virus (LCMV), topologically associating domains (TADs), CTCF (CCCTC -binding factor), CTCF binding sites (CBSs), lineage-determining transcription factors (LDTFs)