University of Oulu, Asahikawa Medical University, International University of Health and Welfare, Tokyo, International University of Health and Welfare, Tokyo, Karolinska Institutet, Chiba University, International University of Health and Welfare, Tokyo, International University of Health and Welfare, Tokyo, Asahikawa Medical University, Tokai University, Asahikawa Medical University, International University of Health and Welfare, Tokyo, Karolinska Institutet - Department of Oncology-Pathology, University of Oulu and University of Oulu