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John A. Flygare

Merck & Co., Inc. - Department of Discovery Chemistry

SCHOLARLY PAPERS

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Scholarly Papers (1)

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In vivo Bioluminescence Imaging of Labile Iron in Xenograft Models and Liver Using FeAl-1, an Iron-Activatable Form of D-Luciferin

Number of pages: 46 Posted: 18 Nov 2022
Ryan L. Gonciarz, Honglin Jiang, Cedric L. Hugelshofer, Oscar Ekpenyong, Ian Knemeyer, John A. Flygare, Eric A. Collisson and Adam R. Renslo
University of California, San Francisco (UCSF) - Department of Pharmaceutical Chemistry, University of California, San Francisco (UCSF) - Helen Diller Family Comprehensive Cancer Center, Merck & Co., Inc. - Department of Discovery Chemistry, Merck & Co., Inc. - ADME & Discovery Toxicology, Merck & Co., Inc. - ADME & Discovery Toxicology, Merck & Co., Inc. - Department of Discovery Chemistry, University of California, San Francisco (UCSF) - Helen Diller Family Comprehensive Cancer Center and University of California, San Francisco (UCSF) - Department of Pharmaceutical Chemistry
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Abstract:

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bioluminescence imaging, chemical probes, pancreatic ductal adenocarcinoma, ferroptosis