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Kota Kawamura

Tokyo University of Science

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Fine-Tuning of Nitrogen-Containing Bisphosphonate Esters that Potently Induce Degradation of HMG-CoA Reductase

Number of pages: 42 Posted: 12 Dec 2022
Kota Kawamura, Hiromasa Yoshioka, Chikako Sato, Tomoko Yajima, Yuuki Furuyama, Kouji Kuramochi and Kenji Ohgane
Tokyo University of Science, University of Tokyo - Institute for Quantitative Biosciences, Ochanomizu University, Ochanomizu University, Tokyo University of Science, Tokyo University of Science - Department of Applied Biological Science and Ochanomizu University
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Abstract:

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cholesterol synthesis, HMG-CoA reductase, protein degradation, structure-activity relationships, fluorine