University of Liverpool - Department of Eye and Vision Science, University of Liverpool - Diabetes & Endocrinology Research and Pain Research Institute, University of Liverpool - Diabetes & Endocrinology Research and Pain Research Institute, University of Liverpool - Diabetes & Endocrinology Research and Pain Research Institute, The University of Manchester - Division of Cardiovascular Sciences, The University of Manchester - Department of Neurology, The University of Manchester - Department of Neurology, The University of Manchester - Department of Neurology, Cornell University - Department of Medicine, Cornell University - Department of Medicine, Cornell University - Department of Medicine, Cornell University - Department of Medicine, Hamad Medical Corporation - Neuroscience Institute, Hamad Medical Corporation - Neuroscience Institute, University of Alberta - Department of Medicine, Hamad Medical Corporation - Geriatric & Memory Clinic, Hamad Medical Corporation - Geriatric & Memory Clinic, The University of Manchester - Division of Cardiovascular Sciences, University of Liverpool - Department of Eye and Vision Science and University of Liverpool - Diabetes & Endocrinology Research and Pain Research Institute

Johns Hopkins University, University of Nottingham - Sir Peter Mansfield Imaging Centre, Cornell University - Department of Medicine, Qatar University, The University of Manchester - Division of Cardiovascular Sciences, University of Toronto, Queensland University of Technology, Queensland University of Technology, affiliation not provided to SSRN, affiliation not provided to SSRN, University of Calgary, affiliation not provided to SSRN, University of Liverpool - Diabetes & Endocrinology Research and Pain Research Institute and The University of Manchester - Division of Cardiovascular Sciences