Heidelberg University - Institute of Pathology, Heidelberg University - Department of Hematology, Oncology and Rheumatology, Heidelberg University - Department of Hematology, Oncology and Rheumatology, Heidelberg University - Institute of Pathology, Heidelberg University - Institute of Pathology, University Medical Center Mainz - Department of Surgery, Saint Josefs Hospital - Department of Surgery, University Medical Center Mainz - Institute of Pathology, University Medical Center Mainz - Institute of Pathology and University Medical Center Mainz - Institute of Pathology