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Brian Gastman

Cleveland Clinic - Department of Plastic Surgery

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Scholarly Papers (1)

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p53-Independent Epigenetic Treatment for Chemo-Refractory Small Cell Lung Cancer: Bio-Rationale and in vivo Proof-of-Principle

Posted: 14 Mar 2023
Sudipta Biswas, Kai Kang, Kwok Peng Ng, Tomas Radivoyevitch, Kurt Schalper, Hua Zhang, Daniel Lindner, Anish Thomas, David MacPherson, Brian Gastman, David Schrump, Kwok-Kin Wong, Vamsi Velcheti and Yogen Saunthararajah
Cleveland Clinic - Department of Translational Hematology & Oncology Research, Cleveland Clinic - Department of Translational Hematology & Oncology Research, Cleveland Clinic - Department of Translational Hematology & Oncology Research, Cleveland Clinic - Department of Quantitative Health Sciences, Yale University - Department of Pathology, New York University (NYU) - Thoracic Oncology Program, Cleveland Clinic - Department of Translational Hematology & Oncology Research, National Institutes of Health - Developmental Therapeutics Branch, Fred Hutchinson Cancer Research Center, Cleveland Clinic - Department of Plastic Surgery, Government of the United States of America - Thoracic Epigenetics Section, New York University (NYU) - Thoracic Oncology Program, New York University (NYU) - Thoracic Oncology Program and Cleveland Clinic - Department of Translational Hematology & Oncology Research

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small cell lung cancer, Immune checkpoint blockade, Pyrimidine metabolism, Decitabine, 5azacytidine, Tetrahydrouridine.