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Priyanka Rajan

Roswell Park Comprehensive Cancer Center - Department of Cancer Genetics and Genomics

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A Synergistic Two-Drug Therapy Specifically Targets a DNA Repair Dysregulation That Occurs in p53-Deficient Colorectal and Pancreatic Cancers

Number of pages: 38 Posted: 12 Apr 2023
Mohammed Alruwaili, Justin Zonneville, Hannah Serio, Thomas Melendy, Robert Straubinger, Bryan Gillard, Barbara A. Foster, Priyanka Rajan, Sarah Chatley, Renuka Iyer, Christos Fountzilas and Andrei V. Bakin
Roswell Park Comprehensive Cancer Center - Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center - Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center - Department of Cancer Genetics and Genomics, State University of New York (SUNY) - Department of Microbiology and Immunology, Roswell Park Comprehensive Cancer Center - Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center - Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center - Department of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center - Department of Cancer Genetics and Genomics, Roswell Park Comprehensive Cancer Center - Department of Medicine, Roswell Park Comprehensive Cancer Center - Department of Medicine, Roswell Park Comprehensive Cancer Center - Department of Medicine and Roswell Park Comprehensive Cancer Center - Department of Cancer Genetics and Genomics
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pancreatic cancer, colorectal cancer, poly (ADP-ribose) polymerase, DNA damage, 5-fluorodeoxyuridine, PARP inhibitor, TAS102, trifluorothymidine, base excision repair