Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Massachusetts Institute of Technology (MIT) - Department of Biological Engineering, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard University - Department of Biomedical Informatics, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard University - Center for Functional Cancer Epigenetics, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Baylor University - Lester and Sue Smith Breast Center, Azienda USL Toscana Centro - Bioinformatics Unit, Harvard University - Department of Oncologic Pathology, Harvard T.H. Chan School of Public Health - Department of Biostatistics, Baylor University - Department of Molecular and Cellular Biology, Harvard University - Lurie Family Imaging Center, Harvard University - Department of Oncologic Pathology, Azienda USL Toscana Centro - Sandro Pitigliani Translational Research Unit, Harvard University - Department of Cancer Biology, Harvard University - Department of Cancer Biology, Harvard University - Department of Data Science, Baylor University - Lester and Sue Smith Breast Center, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard University - Department of Medical Oncology, Dana-Farber Cancer Institute and Independent

affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Heidelberg University - University Hospital Heidelberg, affiliation not provided to SSRN, Heidelberg University - Central Institute of Mental Health, affiliation not provided to SSRN, Heidelberg University - Central Institute of Mental Health, University of Queensland, QIMR Berghofer Medical Research Institute, Heidelberg University - University Hospital Heidelberg, Heidelberg University - University Hospital Heidelberg, Technische Universität München (TUM) - Department of Neurosurgery, Harvard University - Department of Data Science, affiliation not provided to SSRN and affiliation not provided to SSRN