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J. Fraser Glickman

Rockefeller University - Fisher Drug Discovery Resource Center

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High-Throughput Screening Identifies Small Molecule Inhibitors of Thioesterase Superfamily Member 1: Implications for the Management of Non-Alcoholic Fatty Liver Disease

Number of pages: 89 Posted: 28 Apr 2023
Christopher S. Krumm, Renee S. Landzberg, Lavoisier Ramos-Espiritu, Carolina Adura, Xu Liu, Mariana Acuna, Yang Xie, Xu Xu, Matthew C. Tillman, Yingxia Li, J. Fraser Glickman, Eric Ortlund, John D. Ginn and David E. Cohen
Cornell University - Division of Gastroenterology & Hepatology, Cornell University - Division of Gastroenterology & Hepatology, Rockefeller University - Fisher Drug Discovery Resource Center, Rockefeller University - Fisher Drug Discovery Resource Center, Emory University - Department of Biochemistry, Harvard University - Division of Gastroenterology, Hepatology and Endoscopy, Harvard University - Division of Gastroenterology, Hepatology and Endoscopy, Cornell University - Division of Gastroenterology & Hepatology, Emory University - Department of Biochemistry, Cornell University - Division of Gastroenterology & Hepatology, Rockefeller University - Fisher Drug Discovery Resource Center, Emory University - Department of Biochemistry, Tri-Institutional Therapeutics Discovery Institute and Cornell University - Division of Gastroenterology & Hepatology
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acyl-CoA thioesterase, lipid metabolism, energy homeostasis, brown adipose tissue, obesity associated metabolic disorders, insulin resistance