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Alex J. Lee

Johns Hopkins University - Bloomberg-Kimmel Institute for Cancer Immunotherapy

Baltimore, MD 21287

United States

  • Johns Hopkins University - Bloomberg-Kimmel Institute for Cancer Immunotherapy

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Metabolic Reprogramming of Tumor Associated Macrophages Using Glutamine Antagonist JHU083 Drives Tumor Immunity in Myeloid-Rich Prostate and Bladder Cancer Tumors

Number of pages: 52 Posted: 12 Jul 2023
Monali Praharaj, Fan Shen, Alex J. Lee, Liang Zhao, Thomas R. Nirschl, Debebe Theodros, Alok K. Singh, Xiaoxu Wang, Kenneth M. Adusei, Kara Lombardo, Raekwon A. Williams, Laura A. Sena, Elizabeth Thompson, Ada Tam, Srinivasan Yegnasubramanian, Edward J. Pearce, Robert D. Leone, Jesse Alt, Rana Rais, Barbara S. Slusher, Drew M. Pardoll, Jonathan D. Powell and Jelani C. Zarif
Johns Hopkins University - Bloomberg-Kimmel Institute for Cancer Immunotherapy, affiliation not provided to SSRN, Johns Hopkins University - Bloomberg-Kimmel Institute for Cancer Immunotherapy, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Johns Hopkins University - Department of Urology, affiliation not provided to SSRN, Johns Hopkins University - Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University - Department of Medicine, affiliation not provided to SSRN, Johns Hopkins University - Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University - Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University - Bloomberg-Kimmel Institute for Cancer Immunotherapy, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Johns Hopkins University - Bloomberg-Kimmel Institute for Cancer Immunotherapy, affiliation not provided to SSRN and Johns Hopkins University - Bloomberg-Kimmel Institute for Cancer Immunotherapy
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Abstract:

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tumor associated macrophages, macrophages, glutamine, JHU083, prostate cancer, bladder cancer