University of Castilla-La Mancha, University of Castilla-La Mancha, UGC Primary Care, San Roque, University Hospital of Jerez, Instituto de Investigacion Biomédica de Cádiz (INiBICA), University Hospital of Jerez, University Hospital of Jerez, University Hospital of Jerez, University Hospital of Jerez, University of Castilla-La Mancha, University of Castilla-La Mancha, University Hospital of Jerez and University of Castilla-La Mancha