Bocconi University, University of Glasgow, University of Bristol, Independent, University of Edinburgh, University of Bristol - NIHR Bristol and Western Biomedical Research Centre, University of Bristol - Centre for Surgical Research, University of Toronto - The Hospital for Sick Children - SickKids, University of Leicester, University of Toronto, National Institute for Health and Clinical Excellence (NHS), University of Toronto - Child Health Evaluative Sciences, AstraZeneca Pharmaceuticals, University of Southern Denmark, Basel University - CLEAR Methods Center, European Institute of Oncology (IEO) IRCCS - Division of Thoracic Surgery, University of Bristol - Bristol Heart Institute and Translational Biomedical Research Centre, University of Galway, Federal University of Minas Gerais (UFMG), Fred Hutchinson Cancer Research Center - Vaccine and Infectious Disease Division, Independent, University of New South Wales (UNSW), Università degli Studi di Genova, King's College London, George Washington University, Iran University of Medical Sciences - Rajaie Cardiovascular Medical and Research Center, University of Bordeaux - CHU de Bordeaux, Charité–Universitätsmedizin Berlin, Cleveland Clinic, McMaster University, Cleveland Clinic, Independent, Bispebjerg and Frederiksberg Hospitals - Section for Biostatistics and Evidence-Based Research, University of Oxford, Yale University and University of Glasgow