University of Milan - Pediatric Clinical Research Center Fondazione Romeo ed Enrica Invernizzi, University of Milan, Harvard University - Division of Nephrology, University of Milan, Magna Graecia University of Catanzaro, University of Milan, University of Milan, Huazhong University of Science and Technology - Tongji Hospital, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Pediatric Nephrology, Dialysis and Transplantation Unit, University Of Milan, Harvard University - Division of Nephrology, University of Milan - Department of Health Sciences, University of Milan - Pediatric Clinical Research Center Fondazione Romeo ed Enrica Invernizzi, University of Milan - Pediatric Clinical Research Center Fondazione Romeo ed Enrica Invernizzi, University of Milan - Pediatric Clinical Research Center Fondazione Romeo ed Enrica Invernizzi, University of Milan - Pediatric Clinical Research Center Fondazione Romeo ed Enrica Invernizzi, Harvard University - Brigham and Women’s Hospital, Humanitas University, ASST Fatebenefratelli-Sacco University Hospital - Division of Endocrinology, ASST Fatebenefratelli-Sacco University Hospital - Division of Endocrinology, University of Milan - Pediatric Clinical Research Center Fondazione Romeo ed Enrica Invernizzi, University of Milan - Pediatric Clinical Research Center Fondazione Romeo ed Enrica Invernizzi, University of Milan-Bicocca, University of Milan-Bicocca, University of Milan, University of Insubria, Università di Milano - Nanomedicine Laboratory, University of Milan, University of Milan, University of Milan, Boston Children’s Hospital/Harvard Medical School - Pulmonary Medicine, Boston Children’s Hospital/Harvard Medical School - Pulmonary Medicine, Harvard University - Massachusetts General Hospital, Huazhong University of Science and Technology - Department of Pediatrics, University of Parma, University of Insubria, Huazhong University of Science and Technology - Tongji Hospital, Harvard University - Massachusetts General Hospital, University of Milan - Department of Clinical and Biological SciencesUniversity of Milan - Department of Pediatrics, Harvard University - Brigham and Women’s Hospital, ASST Santi Paolo e Carlo and ASST Fatebenefratelli-Sacco University Hospital - Division of Endocrinology