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Shayuan Khazaei

University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia

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Scholarly Papers (1)

1.

Age-Specific Induction of Mutant p53 in Hematopoietic Stem Cells Drives Clonal Hematopoiesis in Adult Mice Leading to Acute Myeloid Leukemia

Number of pages: 44 Posted: 30 Aug 2023
University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia, The Francis Crick Institute - Cancer Genomics Laboratory, University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia, University of Texas at Houston - Department of Epigenetics and Molecular Carcinogenesis, University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia, University of Nebraska at Omaha - Department of Pathology and Microbiology, University of Texas at Houston - Department of Veterinary Medicine and Surgery, The Francis Crick Institute - Cancer Genomics Laboratory and University of Texas at Houston - Section of Molecular Hematology and Therapy, Department of Leukemia
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Abstract:

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TP53 mutations, Clonal hematopoiesis (CH), Acute myeloid leukemia (AML), Mdm2 haploinsufficiency, Myeloid-biased hematopoiesis, Hematopoietic stem cells