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Ann Daly

Newcastle University - Translational and Clinical Research Institute

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Higher Hepatic Glucose Production and Gluconeogenesis are Features of Severe Metabolic Dysfunction-Associated Steatohepatitis Even in Absence of T2D

Number of pages: 31 Posted: 13 Sep 2023
Silvia Sabatini, Partho Sen, Fabrizia Carli, Samantha Pezzica, Chiara Rosso, Erminia Lembo, Ornella Verrastro, Ann Daly, Olivier Govaere, Simon Cockel, Tuulia Hyötyläinen, Geltrude Mingrone, Elisabetta Bugianesi, Quentin M. Anstee, Matej Orešič and Amalia Gastaldelli
National Research Council (CNR), Technische Universität München (TUM), National Research Council (CNR), National Research Council (CNR), University of Turin - Department of Medical Sciences, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Newcastle University - Translational and Clinical Research Institute, Newcastle University - Translational and Clinical Research Institute, Newcastle University - Translational and Clinical Research Institute, Örebro University, Catholic University of Milan - Fondazione Policlinico Universitario Agostino Gemelli, University of Turin - Division of Gastroenterology, University of Newcastle (Australia), Örebro University and National Research Council (CNR)
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Abstract:

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steatotic liver disease, type 2 diabetes, genome-scale metabolic modeling, fluxomics, hepatic glucose production, gluconeogenesis, insulin resistance