Sven Golfier

Bayer AG

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Novel YAP1/TAZ Pathway Inhibitors Identified Through Phenotypic Screening with Potent Anti-Tumor Activity via Blockade of GGTase-I / Rho-GTPase Signaling

Number of pages: 65 Posted: 25 Sep 2023
Keith Graham, Philip Lienau, Benjamin Bader, Stefan Prechtl, Jan Naujoks, Ralf Lesche, Julia Kuehnlenz, Krzysztof Brzezinka, Lisette Potze, Francesca Zanconato, Barbara Nicke, Anna Montebaur, Wilhelm Bone, Sven Golfier, Stefan Kaulfuss, Charlotte Kopitz, Sabine Pilari, Holger Steuber, Sikander Hayat, Atanas Kamburov, Andreas Steffen, Andreas Schlicker, Philipp Buchgraber, Nico Braeuer, Nuria Aiguabella Font, Tobias Heinrich, Lara Kuhnke, Katrin Nowak-Reppel, Carlo Stresemann, Patrick Steigemann, Annette Walter, Simona Blotta, Matthias Ocker, Ashley Lakner, Dominik Mumberg, Knut Eis, Stefano Piccolo and Martin Lange
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geranylgeranyltransferase I, GGTase I, PGGT1b, Hippo pathway, Rho-GTPase, YAP1, TAZ, WWTR1, Cancer, target deconvolution, Chemical Biology, drug discovery