Instituto Nacional de Saude, Mbeya Medical Research Center, Ludwig Maximilian University of Munich (LMU) - Division of Infectious Diseases and Tropical Medicine, Instituto Nacional de Saúde., University of North Carolina (UNC) at Chapel Hill - National Institute of Health, Mbeya Medical Research Center, University of North Carolina (UNC) at Chapel Hill - National Institute of Health, National Institute for Medical Research (NIMR), National Institute for Medical Research (NIMR), University of North Carolina (UNC) at Chapel Hill - National Institute of Health, University of North Carolina (UNC) at Chapel Hill - National Institute of Health, affiliation not provided to SSRN, National Institute for Medical Research (NIMR), Clinton Health Access Initiative, affiliation not provided to SSRN, Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Ludwig Maximilian University of Munich (LMU) - Division of Infectious Diseases and Tropical Medicine, Egas Moniz - Cooperativa de Ensino Superior CRL - Centro de Investigação Interdisciplinar Egas Moniz (CiiEM), University of California, Los Angeles (UCLA), Ludwig Maximilian University of Munich (LMU) - Division of Infectious Diseases and Tropical Medicine and affiliation not provided to SSRN