Fudan University - Shanghai Pudong Hospital, Fudan University - Department of Endocrinology and Metabolism, Fudan University - Department of Endocrinology and Metabolism, Fudan University - Department of Endocrinology and Metabolism, Fudan University - Department of Endocrinology and Metabolism, University of California, San Francisco (UCSF), Fudan University - Shanghai Pudong Hospital, Fudan University - Shanghai Pudong Hospital, Fudan University - Department of Endocrinology and Metabolism and Fudan University - Shanghai Pudong Hospital