Imperial College London, University of Southampton - School of Clinical and Experimental Sciences, Nanyang Technological University (NTU), University of Amsterdam - University Medical Center, GSK plc, GSK plc, AstraZeneca Pharmaceuticals, Imperial College London, University of Amsterdam - Department of Respiratory Medicine, Karolinska Institutet, University of Southampton, Nanyang Technological University (NTU), University of Southampton, Imperial College London - Airways Disease Section, Imperial College London - National Heart and Lung Institute and Independent