European Organisation for Research and Treatment of Cancer (EORTC), European Organisation for Research and Treatment of Cancer (EORTC), University of Copenhagen - Department of Oncology, Erasmus University Medical Center - Department of Medical Oncology, Indiana University - Melvin and Bren Simon Comprehensive Cancer Center, N.N. Blokhin Russian Cancer Research Center, Université Paris XI Sud - Gustave Roussy Cancer Campus, Lund University - Skåne University Hospital, University Medical Centre Groningen, IRCCS Istituto Romagnolo per lo Studio dei Tumori "Dino Amadori" (IRST) - Clinical and Experimental Oncology Unit, University College London - MRC Clinical Trials Unit, University of Toronto - Princess Margaret Cancer Centre, St. Olavs University Hospital, Royal Marsden NHS Foundation Trust - Department of Oncology, Università Vita-Salute San Raffaele - IRCCS San Raffaele Scientific Institute, University of Adelaide, University of Barcelona - Institut Català d'Oncologia - Hospitalet, IDIBELL, University of Calgary - Tom Baker Cancer Center, University of Zurich - Department of Medical Oncology and Hematology, Medical Faculty Comenius University, Western University, Canada, The University of Sydney - NHMRC Clinical Trials Centre, Memorial Sloan Kettering Cancer Center, Medical University of Graz - Division of Oncology, Ludwig Maximilian University of Munich (LMU) - Department of Hematology and Oncology, University of Hamburg - Department of Hematology, Oncology and Bone Marrow Transplantation with Section of Pneumology, University of Oslo - Department of Oncology, University of Zurich, Government of the United Kingdom - St Bartholomew's Hospital, University of Pennsylvania, San Camillo Forlanini Hospital, University of Cologne - University Hospital of Cologne, European Organisation for Research and Treatment of Cancer (EORTC), Oncology Institute of Southern Switzerland and University of Bern

affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, Government of the United Kingdom - NHS Greater Glasgow and Clyde, Tata Memorial Centre, Royal Marsden NHS Foundation Trust, affiliation not provided to SSRN, Christian Medical College, Tata Medical Center, affiliation not provided to SSRN, Royal Cornwall Hospitals NHS Trust, Southern Medical University - Institute of Cancer Research, University College London - MRC Clinical Trials Unit, affiliation not provided to SSRN and Institute of Cancer Research (ICR) - Radiotherapy and Imaging