Institute of Cancer Research (ICR), Institute of Cancer Research (ICR), University of Oxford, University College Hospital, Oxford University Hospitals NHS Foundation Trust, Imperial College London - Imperial College Healthcare NHS Trust, Cardiff University, Imperial College London - Section of Anaesthetics, Pain Management and Intensive Care, Government of the United Kingdom - Chelsea and Westminster Hospital NHS Foundation Trust, Imperial College London - Department of Infectious Disease, Imperial College London and Institute of Cancer Research (ICR)