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Khaled M. Darwish

Suez Canal University

SCHOLARLY PAPERS

3

DOWNLOADS

197

TOTAL CITATIONS

1

Scholarly Papers (3)

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1.

Development of 1, 2, 3-Triazole Hybrids as Multi-Faced Anticancer Agents Co-Targeting Egfr/Mtor Pathway and Tubulin Depolymerization

Number of pages: 51 Posted: 15 Nov 2024
Mennatallah Ali Shaheen, Khaled M. Darwish, Safaa Mohamed Kishk, Magda Abdel Aziz El-Sayed and Ismail Salama
Horus University, Suez Canal University, affiliation not provided to SSRN, affiliation not provided to SSRN and Suez Canal University
Downloads 83 (783,685)
Citation 1

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Colorectal cancer, 1, 2, 3-Triazole, Chalcones, Pyrazoles, Pyrimidines, EGFR/mTOR pathway, Tubulin Depolymerization, Cell Cycle Arrest, Commputational studies.

2.

Development, Biological Evaluation, and Molecular Modelling of Novel Isocytosine and Guanidine Derivatives as Bace1 Inhibitors Using a Fragment Growing Strategy

Number of pages: 41 Posted: 13 Mar 2024
Asmaa M. Atta, Nouran Rihan, Ahmad M. Abdelwaly, Mohamed S. Nafie, Mohamed S. Elgawish, Samia M. Moustafa, Mohamed A. Helal and Khaled M. Darwish
Badr university in Cairo, Zewail City of Science and Technology, Temple University, University of Sharjah, Suez Canal University, Suez Canal University, Zewail City of Science and Technology and Suez Canal University
Downloads 64 (924,743)

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Alzheimer's disease, BACE1 inhibitors, Aβ42, Molecular Modelling, Cranial/hepatic tissue safety

3.

Discovery of Novel Tris-1,2,3-Triazole-Based Hybrids as Vegfr2 Inhibitors with Potent Anti-Proliferative and Cytotoxicity Through Apoptosis Induction

Number of pages: 80 Posted: 15 Nov 2024
Mosa Alsehli, Adeeb Al Sheikh Ali, Mohamed S. Nafie, Sanaa Bardaweel, Ateyatallah Aljuhani, Khaled M. Darwish, Shaya Yahya Alraqa, Nadjet Rezki and Mohamed Reda Aoaud
Taibah University, Department of Communication Disorders Sciences, American University of Sharjah, University of Jordan, affiliation not provided to SSRN, Suez Canal University, affiliation not provided to SSRN, Taibah University and Taibah University
Downloads 50 (1,074,648)

Abstract:

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Tris-1, 2, 3-Triazoles, Click chemistry, VEGFR2, Apoptosis, Docking