University of Florence - Azienda Ospedaliero Universitaria Careggi, University of Florence - Azienda Ospedaliero Universitaria Careggi, affiliation not provided to SSRN, University Hospital Careggi, University of Florence - Azienda Ospedaliero Universitaria Careggi, University of Florence - Azienda Ospedaliero Universitaria Careggi, affiliation not provided to SSRN, affiliation not provided to SSRN, University Hospital Careggi and affiliation not provided to SSRN