affiliation not provided to SSRN, University of Kansas - Cancer Center, affiliation not provided to SSRN, INCLIVA Biomedical Research Institute, University of Michigan at Ann Arbor, Fred Hutchinson Cancer Research Center - Clinical Research Division, Vanderbilt University - Vanderbilt-Ingram Cancer Center, Netherlands Cancer Institute, Northwestern University - Northwestern Memorial Hospital, Brown University, Emory University - School of Medicine, INCLIVA Biomedical Research Institute, Vanderbilt University - Division of Hematology and Oncology, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN, affiliation not provided to SSRN and Brown University