The Hospital for Sick Children, BC Cancer, University of Ottawa - Ottawa Hospital Research Institute, University of Montreal - Notre-Dame Hospital, Juravinski Hospital - Cancer Centre, Western University, Canada, Cross Cancer Institute, University of British Columbia (UBC), CancerCare Manitoba, University of British Columbia (UBC), University of British Columbia (UBC), University of Toronto - University Health Network, University of Toronto - Princess Margaret Cancer Centre, University of Montreal - Notre-Dame Hospital, University of Ottawa - Ottawa Hospital Research Institute, University of Toronto - Princess Margaret Cancer Centre, University of Toronto - University Health Network, Juravinski Hospital - Cancer Centre, Canadian Cancer Trials Group, Canadian Cancer Trials Group, Canadian Cancer Trials Group and Canadian Cancer Trials Group

affiliation not provided to SSRN, University of Toronto - Sunnybrook Research Institute, affiliation not provided to SSRN, The Hospital for Sick Children and affiliation not provided to SSRN